She then portrayed an institutionalized pathological liar in the acclaimed Girl, Interrupted, as well as a lesbian enrolled in therapy camp in the indie hit But I'm a Cheerleader.
Major roles in The Astronaut's Wife (1999), Ghosts of Mars (2001) and Thirteen Conversations About One Thing (2001) followed.
Du Vall also took promotional pictures for Uh Huh Her.
In 2014, she appeared as Emma Borden on Lifetime's Lizzie Borden Took an Ax later reprised her role in .
She is best known for her role as Sofie on the HBO television series Carnivàle (2003–05), as well as for films such as The Faculty (1998), But I'm a Cheerleader (1999), Girl, Interrupted (1999), and The Grudge (2004).But the other point here, in the new post-lesbian-Jodie era, is that when celebrities have not yet come all the way out—as in, sans public declaration—they may be encouraging even more snooping from paparazzi who likely get paid more when they “out” the private types. Regardless, Du Vall enjoying an afternoon date seems pretty reasonable and markedly normal. Prior to making her debut in Little Witches, she worked in a coffee shop.She appeared in various films and episodes of television shows such as ER and Buffy the Vampire Slayer before her breakthrough role as a goth student in Robert Rodriguez's The Faculty.